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Table 2 Evaluation of Hemostatic effects

From: Analysis of the effect of initial hemostasis resuscitation with recombinant human coagulation factor VII a on the treatment of postoperative hemorrhage in cardiac surgery

 

IHR group(n = 102)

non-IHR group (n = 50)

p-value

Dosage of rFVIIa, µg/kg

29.41 (26.2,34.6)

36.04(28.6,59.3)

0.002

Re-application of rFVIIa, n(%)

18(17.6)

18(36.0)

0.012

Percentage of patients needing blood product, n(%)

41(40.2)

31(62.0)

0.011

Fluid volume administered in 24 h, ml

2612.5(2051.3,3337.5)

3395(2537.5,4395.0)

<0.001

RBC transfusion in 24 h, U

0(0,2)

2(0,6)

0.018

Plasma transfusion in 24 h, ml

0(0,0)

0(0,400)

0.021

Chest tube drainage in 6 h, ml

315(150.0,762.5)

690(400,1162.5)

<0.001

Chest tube drainage in 12 h, ml

600(300.0,1062.5)

1075(600.0,1560.0)

<0.001

Chest tube drainage in 24 h, ml

875(500.0,1340.0)

1500(990.0,2300.0)

<0.001

PLTmin, ×109/L

74.5(58.0,115.0)

33.5(20.9,59.3)

<0.001

D-Dmax, ng/ml

756(415.5,2140.5)

1742.5(675.3,3392.0)

0.003

  1. PLTmin: lowest platelet count; D-Dmax: The highest value of D-dimer