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Table 1 MINS prevention strategies

From: Comprehensive review of myocardial injury after noncardiac surgery: prevention, intervention, and long-term management strategies

MINS Prevention Strategies

Description

Level of Evidence

Risk assessment tools

RCRI

Calculates risk based on high-risk noncardiac surgery, history of ischemic heart disease, CHF, TIA/stroke, preoperative treatment with insulin, and preoperative creatinine over 2 mg/dL

Used to guide postoperative cardiac monitoring,

Has limited predictive accuracy of cardiac events/death, especially following vascular non-cardiac surgeries

ACS-NSQIP

Offers more individualized risk assessment

based on over 135 variables

compares performance to national standards

Reduction of postoperative complications and mortality by 45% and 27%, respectively

may have limited predictive accuracy and surgical bias13

Gupta Perioperative Risk for MICA

Similar to RCRI but more accurate at identifying high-risk patients

Does not overestimate low-risk population

Uses parameters specific to cardiac injury to determine risk of developing MINS

Factors in various surgery types, including minimally invasive, and differentiates them in the context of intra-operative and post-operative MI or cardiac arrest13

Retrospective data likely underestimates amounts of MI reported

VISION risk calculator

Uses the same risk factors assessed in RCRI as well as NT-proBNP levels to predict cardiovascular injury within 30 days post-operation

Provides updated estimates to the RCRI assessment by evaluating perioperative cardiovascular risk up to 30 days after surgery

Limitation of external validation regarding NT-proBNP thresholds within other patient cohorts14

Minimize cardiovascular risk factors

Utilize preoperative cardiac assessment by evaluating functional status, evaluation of daily activities of living, and lab work specifically biomarkers like BNP or NT-proBNP and electrocardiogram, echocardiography, and stress tests if indicated

Risk factor modification

Lifestyle modifications include smoking cessation, a healthy diet, and regular physical activity

Medication management for other comorbid conditions such as hypertension and diabetes mellitus

Patient and provider education

Healthcare providers can impart guidance on lifestyle modifications, the importance of medication adherence, and follow-up appointments with primary caregivers and specialists