Table 5 Demographic information of patients with ESRD and CKD in the REQUEST study
Demographic and clinical characteristics | Normal renal function (N = 921) | CKD/ESRD (N = 95) | P-value |
|---|---|---|---|
Age (years) | 65.7 ± 9.4 | 67.5 ± 10.3 | 0.064 |
Sex (female) | 130 (14.1) | 13 (13.7) | 0.91 |
Body mass index (kg/m2)a | 27.7 (25.2–31.0) | 28.1 (25.6–31.9) | 0.37 |
Prior myocardial infarction | 293 (31.8) | 38 (40.0) | 0.11 |
History of coronary revascularization | 203 (22.0) | 29 (30.5) | 0.061 |
Prior coronary artery bypass grafting | 6 (0.7) | 1 (1.1) | 0.50 |
Prior percutaneous coronary intervention | 200 (21.7) | 29 (30.5) | 0.050 |
History of stroke | 51 (5.5) | 11 (11.6) | 0.019 |
Hypertension | 644 (69.9) | 80 (84.2) | 0.003 |
Hyperlipidemia | 508 (55.2) | 50 (52.6) | 0.64 |
Diabetes mellitus | 352 (38.2) | 50 (52.6) | 0.006 |
Chronic obstructive pulmonary disease | 62 (6.7) | 15 (15.8) | 0.002 |
Carotid artery stenosis | 82 (8.9) | 11 (11.6) | 0.39 |
Peripheral vascular disease | 82 (8.9) | 16 (16.8) | 0.013 |
History of carotid/peripheral vascular intervention | 40 (4.3) | 5 (5.3) | 0.60 |
Atrial fibrillation | 28 (3.0) | 5 (5.3) | 0.23 |
Left-ventricular ejection fraction < 30%b | 16 (1.8) | 8 (8.7) | 0.001 |
Missing | 35 | 3 | |
Canadian Cardiovascular Society angina classification | 0.096 | ||
0 | 102 (11.6) | 18 (19.4) | |
I–II | 410 (46.6) | 39 (41.9) | |
III–IV | 367 (41.8) | 36 (38.7) | |
Missing | 42 | 2 | |
New York Heart Association functional classificationb | 0.20 | ||
I | 324 (38.3) | 25 (28.4) | |
II | 356 (42.0) | 40 (45.5) | |
III | 141 (16.7) | 18 (20.5) | |
IV | 26 (3.1) | 5 (5.7) | |
Left main involvement | 400 (54.7) | 37 (56.1) | 0.83 |