Clinical outcomes of pregnancy in patients with pulmonary hypertension: A single center observational study

Table 3 Characteristics of maternal mortalities

Characters	Case 1	Case 2	Case 3	Case 4	Case 5	Case 6
Age years	27	38	40	30	23	25
Parity	G4P1	G6P3	G5P1	G2P1	G2P1	G1P0
Etiology of disease	PAH-CHD (atrial septal defect)	OPAH	IPAH	PH-CHD (atrial septal defect)	PH-LHD	PAH-CHD (Ventricle septal defect, Patent ductus arterial)
Eisenmenger’ syndrome	Yes	No	No	Yes	No	Yes
Complication	hepatitis	Gestational diabetic melius, Hyperthyroidism	Hydronephrosis, pneumonia	Pulmonary thrombosis	Cardiomyopathy	Pneumonia
NYHA class	IV	IV	IV	IV	IV	IV
S-PABP, mmHg	116	83	167	193	81	130
NT-proBNP, pg/mL	4367	1275	3992	4357	2233	1071
LVEF, %	67	40	57	36	25	52
G. week of diagnose PH	28^+ 4	27^+ 4	12^+ 4	7^+ 2	10^+ 2	22^+ 2
Termination of G. weeks	29^+ 2	28^+ 4	19^+ 3	8^+ 1	10^+ 3	29
Delivery model	Caesarean section	Caesarean section	Abortion	Abortion	Abortion	Caesarean section
Anesthesia model	Epidural	Epidural	General	Epidural	Epidural	General
Timing death	during Delivery	9d Post Delivery	6d Post Delivery	2d Post Delivery	30d Post Delivery	21d post Delivery
Advance therapy	NO	Sildenafil	Bosten	Bosten	NO	Prostaglandin E and Sildenafil
Death reason	Cardiac arrest	Cardiac arrest, Multiple organ failure	Cardiac arrest	Hypoxia	Cardiac shock	Fungal Sepsis
Fetal destiny	Died	Died	Miscarriage	Miscarriage	Miscarriage	survival

PH = pulmonary hypertension, IPAH = idiopathic pulmonary arterial hypertension, PAH-CHD = pulmonary hypertension associated with congenital heart disease, OPAH = other reason pulmonary arterial hypertension, PH-LHD = pulmonary hypertension associated with left heart disease, NYHA = New York heart association, NT-proBNP = N-terminal pro-brain natriuretic peptide, LVEF = Left ventricular ejection fraction, G. week = Gestational week

ISSN: 1749-8090