Fig. 3
From: LncRNA MAGI2-AS3 promotes the progression of atherosclerosis by sponging miR-525-5p
MAGI2-AS3 served as sponge for miR-525-5p. A, B. The potential relationship between MAGI2-AS3 and miR-525-5p was obtained from StarBase (A) and further verified by dual-luciferase (n = 3) (B). C. The distribution of MAGI2-AS3, miR-525-5p, GAPDH, and U6 in the cytoplasmic and nuclear fractions of HCASMCs. D. The serum of miR-525-5p was reduced in AS patients. E. Spearman correlation between MAGI2-AS3 and miR-525-5p was displayed in scatter plot. F. The abundance of miR-525-5p decreased in a dose-dependent manner in ox-LDL-induced HCASMCs (n = 5). Values were presented as mean ± SD (n = 5). *P < 0.05, **P < 0.05, ***P < 0.001 vs. control. AS, atherosclerosis; HCASMCs, human coronary artery smooth muscle cells; ox-LDL, oxidized low-density lipoprotein