Fig. 4
From: LncRNA MAGI2-AS3 promotes the progression of atherosclerosis by sponging miR-525-5p
Down-regulated miR-525-5p reversed the protective effects on cellular function due to si-MAGI2-AS3 under ox-LDL treatment (50 mg/L ox-LDL) in HCASMCs. A. The levels of MAGI2-AS3 and miR-525-5p after transfection. B, C, D. Co-transfected with si-MAGI2-AS3 and miR-525-5p inhibitor increased cell proliferation (B) and migration (C) and decreased the apoptosis (D) compared to transfection si-MAGI2-AS3 alone under ox-LDL treatment in HCASMCs. Values were presented as mean ± SD (n = 5). *P < 0.05, **P < 0.05, ***P < 0.001 vs. control. AS, atherosclerosis; HCASMCs, human coronary artery smooth muscle cells; ox-LDL, oxidized low-density lipoprotein