Fig. 1

Circ-PSMB1 was elevated in ox-LDL-stimulated HAECs. Heatmap (A) and volcano map (B) of the differentially expressed circRNAs in AS. (C) The circ-PSMB1 levels in the serum of AS patients were analyzed by qRT‒PCR. (D) The structure of circ-PSMB1. (E) The circ-PSMB1 and line-PSMB1 levels in HAECs were detected by qRT‒PCR after RnaseR treatment. The circ-PSMB1 level in ox-LDL treated HAECs (F) and smooth muscle cells (G) were detected by RT-qPCR. (H) The location of circ-PSMB1 was tested by FISH assay