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Fig. 6 | Journal of Cardiothoracic Surgery

Fig. 6

From: Circ-PSMB1 knockdown inhibits the pyroptosis of ox-LDL treated human aortic cells via the miR-624-3p/ASC axis

Fig. 6

Upregulation of ASC neutralized the effects of miR-624-3p in ox-LDL-treated HAECs. (A) The ASC levels were measured by qRT‒PCR after ASC vector treatment. After miR-624-3p mimic and ASC transfection, (B) cell viability was measured by MTT assay, (C) the pyroptosis rate was analysed by flow cytometry, (D) LDH levels were measured with the corresponding kit, (E-F) IL-1β and IL-18 levels were determined by qRT‒PCR, and (G) the protein expression levels of NLRP3 and GSDMD-N were analysed by western blotting

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Journal of Cardiothoracic Surgery

ISSN: 1749-8090

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